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美洛昔康
CAS号 71125-38-7
中文别名 4-羟-2-甲基-N-(5-甲基-2-噻唑)-2H-1,2-苯并噻唑-3-酰胺-1,1-二氧化物;美洛昔康钠;4-羟基-2-甲基-N-(5-甲基-2-噻唑基)-2H-L,2-苯并噻嗪-3-羧酰胺1,1-二氧化物;美罗昔康;4-羟基-2-甲基-N-(5-甲基-2-噻唑)-2H-1,2-苯并噻嗪-3-甲酰胺 1,1-二氧化物;美洛昔康/4-羟基-2-甲基-N-(5-甲基-1,3-噻唑-2-基)-2H-1,2-苯并噻嗪-3-羧酸乙酯1,1-二氧化物
英文别名 4-Hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazin-3-crboxamide 1,1-dioxide
分子量 351.40
分子式 C14H13N3O4S2
EINECS编号
综合信息 查看供应
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美洛昔康化学性质

熔点 255 °C
储存条件 0-6°C

产品用途

用途 非甾体抗炎药。用于治疗骨关节炎、风湿性关节炎。
用途 关节炎、类风湿关节炎药。
用途 用于类风湿性关节炎、疼痛性骨关节炎的治疗


美洛昔康安全说明书(MSDS)

类别 有毒物质
毒性分级 高毒
急性毒性 口服- 大鼠 LD50 84 毫克/ 公斤; 口服- 小鼠 LD50: 470 毫克/公斤
可燃性危险特性 可燃, 火场排出氮氧化物, 硫氧化物辛辣刺激烟雾
储运特性 库房低温, 通风, 干燥; 与食品原料分开存放; 专门机构保管
灭火剂 水, 二氧化碳, 干粉, 砂土

安全术语
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
不慎与眼睛接触后,请立即用大量清水冲洗并征求医生意见。
风险术语
R22 Harmful if swallowed.
吞食有害。
R36/37/38 Irritating to eyes, respiratory system and skin.
刺激眼睛、呼吸系统和皮肤。
上游原料
methyl 2-(1,1,3-trioxo-1,3-dihydro-2H-1,2-benzisothiazol-2-yl)acetatemethyl 4-hydroxy-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxidemethyl 4-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda(6),2-benzothiazine-3-carboxylate5-Methyl-2-thiazolamine; 5-methyl-1,3-thiazol-2-ylamine; 5-methyl-1,3-thiazol-2-amine; 2-amino-5-methylthiazolebenzenesulfonyl chlorideN-methylbenzenesulfonamidediethyl 2-(N-methylphenylsulfonamido)malonatemethyl 4-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda(6),2-benzothiazine-3-carboxylate1H-1,2-Benzisothiazole-1,1,3(2H)-trione; Saccharinisopropyl 2-(1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)acetateisopropyl 4-hydroxy-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxideisopropyl 4-hydroxy-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide5-Methyl-2-thiazolamine; 5-methyl-1,3-thiazol-2-ylamine; 5-methyl-1,3-thiazol-2-amine; 2-amino-5-methylthiazole1-propanolpropionaldehyde3,3-dibromopropanal5-Methyl-2-thiazolamine; 5-methyl-1,3-thiazol-2-ylamine; 5-methyl-1,3-thiazol-2-amine; 2-amino-5-methylthiazolemethyl 4-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda(6),2-benzothiazine-3-carboxylate1H-1,2-Benzisothiazole-1,1,3(2H)-trione; Saccharinmethyl 2-(1,1,3-trioxo-1,3-dihydro-2H-1,2-benzisothiazol-2-yl)acetatemethyl 4-hydroxy-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxideisopropyl 4-hydroxy-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide5-Methyl-2-thiazolamine; 5-methyl-1,3-thiazol-2-ylamine; 5-methyl-1,3-thiazol-2-amine; 2-amino-5-methylthiazolemethyl 4-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda(6),2-benzothiazine-3-carboxylate5-Methyl-2-thiazolamine; 5-methyl-1,3-thiazol-2-ylamine; 5-methyl-1,3-thiazol-2-amine; 2-amino-5-methylthiazole methyl 2-chloroacetate; methyl chloroacetate methyl 4-hydroxy-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxidemethyl 4-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda(6),2-benzothiazine-3-carboxylate5-Methyl-2-thiazolamine; 5-methyl-1,3-thiazol-2-ylamine; 5-methyl-1,3-thiazol-2-amine; 2-amino-5-methylthiazole1H-1,2-Benzisothiazole-1,1,3(2H)-trione; Saccharinmethyl 4-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda(6),2-benzothiazine-3-carboxylate5-Methyl-2-thiazolamine; 5-methyl-1,3-thiazol-2-ylamine; 5-methyl-1,3-thiazol-2-amine; 2-amino-5-methylthiazole