| Amvuttra | | vutrisiran | To treat polyneuropathy of hereditary transthyretin-mediated amyloidosis | | | 2022-06-13 | Alnylam Pharmaceuticals, Inc |
| Vtama | NME | tapinarof | To treat plaque psoriasis | | | 2022-05-23 | DERMAVANT SCIENCES INC |
| Mounjaro | NME | tirzepatide | To improve blood sugar control in diabetes, in addition to diet and exercise | Press Release | | 2022-05-13 | ELI LILLY AND CO |
| Voquezna | NME | vonoprazan, amoxicillin, and clarithromycin | To treat Helicobacter pylori infection | | | 2022-05-03 | Phathom Pharmaceuticals, Inc |
| Camzyos | NME | mavacamten | To treat certain classes of obstructive hypertrophic cardiomyopathy | | | 2022-04-28 | MYOKARDIA INC |
| Vivjoa | Biologics | oteseconazole | To reduce the incidence of recurrent vulvovaginal candidiasis (RVVC) in females with a history of RVVC who are not of reproductive potential | | | 2022-04-26 | MYCOVIA PHARMACEUTICALS INC |
| Pluvicto | NME | lutetium (177Lu) vipivotide tetraxetan | To treat prostate-specific membrane antigen-positive metastatic castration-resistant prostate cancer following other therapies | | | 2022-03-23 | AAA USA NOVARTIS |
| Opdualag | Biologics | nivolumab and relatlimab-rmbw | To treat unresectable or metastatic melanoma | | | 2022-03-18 | BRISTOL MYERS SQUIBB |
| Ztalmy | NME | ganaxolone | To treat seizures in cyclin-dependent kinase-like 5 deficiency disorder | | | 2022-03-18 | Marinus
Pharmaceuticals, Inc |
| Vonjo | NME | pacritinib | To treat intermediate or high-risk primary or secondary myelofibrosis in adults with low platelets | | | 2022-02-28 | CTI BIOPHARMA CORP |
| Pyrukynd | NME | mitapivat | To treat hemolytic anemia in pyruvate kinase deficiency | | | 2022-02-17 | AGIOS PHARMS INC |
| Enjaymo | Biologics | sutimlimab-jome | To decrease the need for red blood cell transfusion due to hemolysis in cold agglutinin disease | | | 2022-02-04 | BIOVERATIV THERAPEUTICS INC |
| Vabysmo | Biologics | faricimab-svoa | To treat neovascular (wet) aged-related macular degeneration and diabetic macular edema | | | 2022-01-28 | GENENTECH INC |
| Kimmtrak | Biologics | tebentafusp-tebn | To treat unresectable or metastatic uveal melanoma | | | 2022-01-25 | IMMUNOCORE LTD |
| Cibinqo | NME | abrocitinib | To treat refractory, moderate-to-severe atopic dermatitis | | | 2022-01-14 | PFIZER |
| Quviviq | NME | daridorexant | To treat insomnia | | | 2022-01-07 | IDORSIA PHARMACEUTICALS LTD. |
| Adbry | Biologics | tralokinumab-ldrm | To treat moderate-to-severe atopic dermatitis | | | 2021-12-27 | LEO PHARMA AS |
| Leqvio | NME | inclisiran | To treat heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease as an add-on therapy | | | 2021-12-22 | NOVARTIS |
| Tezspire | Biologics | tezepelumab-ekko | To treat severe asthma as an add-on maintenance therapy | | | 2021-12-17 | ASTRAZENECA AB |
| Vyvgart | Biologics | efgartigimod alfa-fcab | To treat generalized myasthenia gravis | Press Release | | 2021-12-17 | ARGENX BV |
