上游原料
ethyl 2-pyridinecarboxylatehydrazine2-pyridinecarbohydrazideEthyl 2-chloro-2-oxoacetate; Ethyl oxalyl chlorideethyl 5-(pyridin-2-yl)-1,3,4-thiadiazole-2-carboxylateiodo(methyl)magnesium1-(5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl)ethan-1-one1-(5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl)ethan-1-ol1-(5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl)ethyl methanesulfonate2-(1-bromoethyl)-5-(pyridin-2-yl)-1,3,4-thiadiazole(3R,3aS,4R,6R,8R,9R,10S,11S,12R,15R,15aS,E)-9-(((2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-((triethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-15-ethyl-N',11-dihydroxy-8-methoxy-4,6,8,10,12,15a-hexamethyl-2,5,13-trioxotetradecahydro-2H-furo[2,3-c][1]oxacyclotetradecine-3-carboximidamide(3R,3aS,4R,6R,8R,9R,10S,11S,12R,15R,15aS,E)-9-(((2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-((triethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-15-ethyl-11-hydroxy-8-methoxy-4,6,8,10,12,15a-hexamethyl-2,5,13-trioxo-N'-(1-(5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl)ethoxy)tetradecahydro-2H-furo[2,3-c][1]oxacyclotetradecine-3-carboximidamide(3R,3aS,4R,6R,8R,9R,10R,12R,15R,15aS,E)-9-(((2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-((triethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-15-ethyl-8-methoxy-4,6,8,10,12,15a-hexamethyl-2,5,11,13-tetraoxo-N'-(1-(5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl)ethoxy)tetradecahydro-2H-furo[2,3-c][1]oxacyclotetradecine-3-carboximidamide(3R,3aS,4R,6R,8R,9R,10R,12R,15R,15aS,E)-9-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-15-ethyl-8-methoxy-4,6,8,10,12,15a-hexamethyl-2,5,11,13-tetraoxo-N'-(1-(5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl)ethoxy)tetradecahydro-2H-furo[2,3-c][1]oxacyclotetradecine-3-carboximidamide(3R,4S,5S,6R,7R,9R,11R,12S,13S,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-4-(((2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione(3R,4S,5S,6R,7R,9R,11R,12S,13S,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-((triethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-7-methoxy-4-(((2S,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-((triethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione(3aR,4R,7R,8S,9S,10R,11R,13R,15R,15aS)-10-(((2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-((triethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-4-ethyl-11-methoxy-8-(((2S,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-((triethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3a,7,9,11,13,15-hexamethyldecahydro-6H-[1,3]dioxolo[4,5-c][1]oxacyclotetradecine-2,6,14(7H)-trione(3R,4S,5S,6R,7R,9R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-((triethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-13-hydroxy-7-methoxy-4-(((2S,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-((triethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradec-11-ene-2,10-dione2-Chloroacetic acid; Chloroacetic AcidCyanoacetic Acid; 2-Cyanoacetic acid2-Chloroacetic anhydride; (Bischloroacetic acid) anhydride; Chloracetic anhydride; Chloroacetic acid anhydride(2R,3S,7R,9R,10R,11S,12S,13R,E)-10-(((2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-((triethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-9-methoxy-12-(((2S,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-((triethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyl-6,14-dioxooxacyclotetradec-4-en-3-yl 2-chloroacetate(2R,3S,7R,9R,10R,11S,12S,13R,E)-10-(((2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-((triethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-9-methoxy-12-(((2S,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-((triethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyl-6,14-dioxooxacyclotetradec-4-en-3-yl 2-cyanoacetate(3R,3aS,4R,6R,8R,9R,10S,11S,12R,15R,15aS)-9-(((2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-((triethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-15-ethyl-8-methoxy-11-(((2S,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-((triethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-4,6,8,10,12,15a-hexamethyl-2,5,13-trioxotetradecahydro-2H-furo[2,3-c][1]oxacyclotetradecine-3-carbonitrile(3R,3aS,4R,6R,8R,9R,10S,11S,12R,15R,15aS)-9-(((2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-((triethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-15-ethyl-11-hydroxy-8-methoxy-4,6,8,10,12,15a-hexamethyl-2,5,13-trioxotetradecahydro-2H-furo[2,3-c][1]oxacyclotetradecine-3-carbonitrileHydroxylamine hydrochloride; Hydroxylammonium chloride; Oxammonium hydrochloride(R)-1-(5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl)ethyl 4-nitrobenzenesulfonate(3R,3aS,4R,6R,8R,9R,10S,11S,12R,15R,15aS,E)-9-(((2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-((triethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-15-ethyl-11-hydroxy-8-methoxy-4,6,8,10,12,15a-hexamethyl-2,5,13-trioxo-N'-((S)-1-(5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl)ethoxy)tetradecahydro-2H-furo[2,3-c][1]oxacyclotetradecine-3-carboximidamide(3R,3aS,4R,6R,8R,9R,10R,12R,15R,15aS,E)-9-(((2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-((triethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-15-ethyl-8-methoxy-4,6,8,10,12,15a-hexamethyl-2,5,11,13-tetraoxo-N'-((S)-1-(5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl)ethoxy)tetradecahydro-2H-furo[2,3-c][1]oxacyclotetradecine-3-carboximidamidemethyl (R)-2-((tert-butyldimethylsilyl)oxy)propanoate(R)-2-((tert-butyldimethylsilyl)oxy)propanehydrazide2-pyridinecarboxylic acid；picolinic acid;Pyridine-2-carboxylic acid(R)-N'-(2-((tert-butyldimethylsilyl)oxy)propanoyl)picolinohydrazide(R)-2-(1-((tert-butyldimethylsilyl)oxy)ethyl)-5-(pyridin-2-yl)-1,3,4-thiadiazole(R)-1-(5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl)ethan-1-ol
