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齐多夫定
CAS号 30516-87-1
中文别名 3'-叠氮-3'-脱氧胸苷; 3'-叠氮-3'-脱氧胸甙
英文别名 3-Azido-3-deoxy-thymidine; azidothymidine; 3'-azido-3'-deoxythymidine; 1-(4-azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1h-pyrimidine-2,4-dione
分子量 267.24
分子式 C10H13N5O4
EINECS编号
综合信息 查看供应
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介多夫定物理化学性质

熔点:106-112°C溶解性:1-5 g/100 mL at 17°C

介多夫定产品用途

用作抗艾滋病和抗病毒药

安全术语
S36/37/39Wear suitable protective clothing, gloves and eye/face protection.
穿戴适当的防护服、手套和护目镜或面具。
S45In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
若发生事故或感不适,立即就医(可能的话,出示其标签)。
风险术语
R40 Limited evidence of a carcinogenic effect.
少数报道有致癌后果。
上游原料
(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)potassium1-[(2R,4S,5R)-4-Hydroxy-5-[(trityloxy)methyl]tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione(1R,9R,10R)-4-Methyl-10-[(trityloxy)methyl]-8,11-dioxa-2,6-diazatricyclo[7.2.1.0(2,7)]dodeca-3,6-dien-5-one(2R,3S,5R)-5-[5-methyl-2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl]-2-[(trityloxy)methyl]tetrahydro-3-furanyl methanesulfonate1-[4-azido-5-[(trityloxy)methyl]tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedioneThymidine; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione(1R,9S,10R)-10-(hydroxymethyl)-4-methyl-8,11-dioxa-2,6-diazatricyclo[7.2.1.0(2,7)]dodeca-3,6-dien-5-one; 2,3'-Anhydrothymidine; 2,3'-2,3'-Anhydrothimidine1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; 5-Methyluridine[(2R,3R,4R,5R)-3-(acetoxy)-4-bromo-5-[5-methyl-2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl]tetrahydro-2-furanyl]methyl acetateThymidine; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione((2S,5S)-8-methyl-9-oxo-2,3-dihydro-5H,9H-2,5-methanopyrimido[2,1-b][1,5,3]dioxazepin-3-yl)methyl 4-methoxybenzoate(3-azido-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl 4-methoxybenzoate5-methyl-2,4-bis[(trimethylsilyl)oxy]pyrimidine; 5-methyl-2-[(trimethylsilyl)oxy]-4-pyrimidinyl trimethylsilyl ether5-(acetoxymethyl)tetrahydrofuran-2,3,4-triyl triacetate1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; 5-MethyluridineEthyl 2-methyl-3-oxopropanoate5-Methyl-2,4(1H,3H)-pyrimidinedione; Thymine5-methyl-2,4-bis[(trimethylsilyl)oxy]pyrimidine; 5-methyl-2-[(trimethylsilyl)oxy]-4-pyrimidinyl trimethylsilyl etherethyl propionateAdenosine; (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydro-3,4-furandiol5-(acetoxymethyl)tetrahydrofuran-2,3,4-triyl triacetate
下游产品