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上游原料
(4aR,6R,7R,8R,8aS)-6-(allyloxy)-7-amino-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxin-8-ol(4aR,6R,7R,8R,8aS)-6-(allyloxy)-7-azido-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxin-8-ol3-(benzyloxy)propyl methanesulfonate(4aR,6R,7R,8R,8aS)-6-(allyloxy)-7-azido-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxin-8-yl (3R)-3-(benzyloxy)tetradecyl ether; (4aR,6R,7R,8R,8aS)-6-(allyloxy)-7-azido-8-{[(3R)-3-(benzyloxy)tetradecyl]oxy}-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxine(4aR,7R,8R,8aS)-7-azido-8-{[(3R)-3-(benzyloxy)tetradecyl]oxy}-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxin-6-ol(4aR,6R,7R,8R,8aS)-7-azido-8-[3-(benzyloxy)propoxy]-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxin-6-yl 2,2,2-trichloroethanimidoate(4aR,6S,7R,8R,8aS)-7-azido-8-{[(3R)-3-(benzyloxy)tetradecyl]oxy}-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxine-6-carbonitrile(4aR,6S,7R,8R,8aS)-7-amino-8-{[(3R)-3-(benzyloxy)tetradecyl]oxy}-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxine-6-carbonitrile(3R)-3-(benzyloxy)tetradecanoic acid(3R)-N-((4aR,6S,7R,8R,8aS)-8-{[(3R)-3-(benzyloxy)tetradecyl]oxy}-6-cyano-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxin-7-yl)-3-(benzyloxy)tetradecanamidebenzhydryl (2S,3R,4R,5S,6R)-3-{[(3R)-3-(benzyloxy)tetradecanoyl]amino}-4-{[(3R)-3-(benzyloxy)tetradecyl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-carboxylate1-(dimethoxymethyl)-4-methoxybenzene(3R)-1,3-tetradecanediol(4R)-2-(4-methoxyphenyl)-4-undecyl-1,3-dioxane; methyl 4-[(4R)-4-undecyl-1,3-dioxan-2-yl]phenyl ether(3R)-3-[(4-methoxybenzyl)oxy]-1-tetradecanol(3R)-3-[(4-methoxybenzyl)oxy]tetradecyl methanesulfonateN-[(4aR,6S,7R,8R,8aS)-6-(allyloxy)-8-hydroxy-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxin-7-yl]-2,2,2-trifluoroacetamideN-((4aR,6S,7R,8R,8aS)-6-(allyloxy)-8-{[(3R)-3-(2-[1,1'-biphenyl]-4-ylethoxy)tetradecyl]oxy}-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxin-7-yl)-2,2,2-trifluoroacetamide(4aR,6S,7R,8R,8aS)-6-(allyloxy)-8-{[(3R)-3-(2-[1,1'-biphenyl]-4-ylethoxy)tetradecyl]oxy}-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxin-7-amine; (4aR,6S,7R,8R,8aS)-6-(allyloxy)-8-{[(3R)-3-(2-[1,1'-biphenyl]-4-ylethoxy)tetradecyl]oxy}-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxin-7-ylamine2,2,2-trichloroethyl (4aR,6S,7R,8R,8aS)-6-(allyloxy)-8-{[(3R)-3-(2-[1,1'-biphenyl]-4-ylethoxy)tetradecyl]oxy}-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxin-7-ylcarbamate2,2,2-trichloroethyl (2S,3R,4R,5S,6R)-2-(allyloxy)-4-{[(3R)-3-(2-[1,1'-biphenyl]-4-ylethoxy)tetradecyl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-ylcarbamatetetradecanoyl chloride2,2,2-trichloroethyl (2S,3R,4R,5S,6R)-2-(allyloxy)-4-{[(3R)-3-(2-[1,1'-biphenyl]-4-ylethoxy)tetradecyl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-ylcarbamate4-{2-[((1R)-1-{2-[((2S,3R,4R,5S,6R)-2-(allyloxy)-6-({[tert-butyl(dimethyl)silyl]oxy}methyl)-5-hydroxy-3-{[(2,2,2-trichloroethoxy)carbonyl]amino}tetrahydro-2H-pyran-4-yl)oxy]ethyl}dodecyl)oxy]ethyl}-1,1'-biphenyl; 2,2,2-trichloroethyl (2S,3R,4R,5S,6R)-2-(allyloxy)-4-{[(3R)-3-(2-[1,1'-biphenyl]-4-ylethoxy)tetradecyl]oxy}-6-({[tert-butyl(dimethyl)silyl]oxy}methyl)-5-hydroxytetrahydro-2H-pyran-3-ylcarbamate4-{2-[((1R)-1-{2-[((2S,3R,4R,5S,6R)-2-(allyloxy)-6-({[tert-butyl(dimethyl)silyl]oxy}methyl)-5-[(diphenoxyphosphoryl)oxy]-3-{[(2,2,2-trichloroethoxy)carbonyl]amino}tetrahydro-2H-pyran-4-yl)oxy]ethyl}dodecyl)oxy]ethyl}-1,1'-biphenyl; 2,2,2-trichloroethyl (2S,3R,4R,5S,6R)-2-(allyloxy)-4-{[(3R)-3-(2-[1,1'-biphenyl]-4-ylethoxy)tetradecyl]oxy}-6-({[tert-butyl(dimethyl)silyl]oxy}methyl)-5-[(diphenoxyphosphoryl)oxy]tetrahydro-2H-pyran-3-ylcarbamate2,2,2-trichloroethyl (2S,3R,4R,5S,6R)-2-(allyloxy)-6-({[tert-butyl(dimethyl)silyl]oxy}methyl)-5-[(diphenoxyphosphoryl)oxy]-4-{[(3R)-3-hydroxytetradecyl]oxy}tetrahydro-2H-pyran-3-ylcarbamate(1R)-1-{2-[((2S,3R,4R,5S,6R)-2-(allyloxy)-6-({[tert-butyl(dimethyl)silyl]oxy}methyl)-5-[(diphenoxyphosphoryl)oxy]-3-{[(2,2,2-trichloroethoxy)carbonyl]amino}tetrahydro-2H-pyran-4-yl)oxy]ethyl}dodecyl myristate(1R)-1-{2-[((2S,3R,4R,5S,6R)-2-(allyloxy)-5-[(diphenoxyphosphoryl)oxy]-6-(hydroxymethyl)-3-{[(2,2,2-trichloroethoxy)carbonyl]amino}tetrahydro-2H-pyran-4-yl)oxy]ethyl}dodecyl myristate2,2,2-trichloroethyl (2S,3R,4R,5S,6R)-2-(allyloxy)-5-[(diphenoxyphosphoryl)oxy]-4-{[(3R)-3-(formyloxy)tetradecyl]oxy}-6-(methoxymethyl)tetrahydro-2H-pyran-3-ylcarbamate(1R)-1-{2-[((2R,3S,4R,5R)-3-[(diphenoxyphosphoryl)oxy]-6-hydroxy-2-(methoxymethyl)-5-{[(2,2,2-trichloroethoxy)carbonyl]amino}tetrahydro-2H-pyran-4-yl)oxy]ethyl}dodecyl myristatebenzhydryl (2S,3R,4R,5S,6R)-3-{[(3R)-3-(benzyloxy)tetradecanoyl]amino}-4-{[(3R)-3-(benzyloxy)tetradecyl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-carboxylate(1R)-1-{2-[((2R,3S,4R,5R)-3-[(diphenoxyphosphoryl)oxy]-6-hydroxy-2-(methoxymethyl)-5-{[(2,2,2-trichloroethoxy)carbonyl]amino}tetrahydro-2H-pyran-4-yl)oxy]ethyl}dodecyl myristate(1R)-1-{2-[((2R,3S,4R,5R)-3-[(diphenoxyphosphoryl)oxy]-2-(methoxymethyl)-6-[(2,2,2-trichloroethanimidoyl)oxy]-5-{[(2,2,2-trichloroethoxy)carbonyl]amino}tetrahydro-2H-pyran-4-yl)oxy]ethyl}dodecyl myristatebenzhydryl (2S,3R,4R,5S,6R)-3-{[(3R)-3-(benzyloxy)tetradecanoyl]amino}-4-{[(3R)-3-(benzyloxy)tetradecyl]oxy}-6-{[((2R,3R,4R,5S,6R)-5-[(diphenoxyphosphoryl)oxy]-6-(methoxymethyl)-4-{[(3R)-3-(tetradecanoyloxy)tetradecyl]oxy}-3-{[(2,2,2-trichloroethoxy)carbonyl]amino}tetrahydro-2H-pyran-2-yl)oxy]methyl}-5-hydroxytetrahydro-2H-pyran-2-carboxylatebenzhydryl (2S,3R,4R,5S,6R)-6-{[((2R,3R,4R,5S,6R)-3-amino-5-[(diphenoxyphosphoryl)oxy]-6-(methoxymethyl)-4-{[(3R)-3-(tetradecanoyloxy)tetradecyl]oxy}tetrahydro-2H-pyran-2-yl)oxy]methyl}-3-{[(3R)-3-(benzyloxy)tetradecanoyl]amino}-4-{[(3R)-3-(benzyloxy)tetradecyl]oxy}-5-hydroxytetrahydro-2H-pyran-2-carboxylatebenzhydryl (2S,3R,4R,5S,6R)-6-{[((2R,3R,4R,5S,6R)-3-(acetylamino)-5-[(diphenoxyphosphoryl)oxy]-6-(methoxymethyl)-4-{[(3R)-3-(tetradecanoyloxy)tetradecyl]oxy}tetrahydro-2H-pyran-2-yl)oxy]methyl}-3-{[(3R)-3-(benzyloxy)tetradecanoyl]amino}-4-{[(3R)-3-(benzyloxy)tetradecyl]oxy}-5-hydroxytetrahydro-2H-pyran-2-carboxylatebenzhydryl (2S,3R,4R,5S,6R)-6-{[((2R,3R,4R,5S,6R)-3-(acetylamino)-5-[(diphenoxyphosphoryl)oxy]-6-(methoxymethyl)-4-{[(3R)-3-(tetradecanoyloxy)tetradecyl]oxy}tetrahydro-2H-pyran-2-yl)oxy]methyl}-3-{[(3R)-3-(benzyloxy)tetradecanoyl]amino}-4-{[(3R)-3-(benzyloxy)tetradecyl]oxy}-5-hydroxytetrahydro-2H-pyran-2-carboxylate(2S,3R,4R,5S,6R)-6-{[((2R,3R,4R,5S,6R)-3-(acetylamino)-5-[(diphenoxyphosphoryl)oxy]-6-(methoxymethyl)-4-{[(3R)-3-(tetradecanoyloxy)tetradecyl]oxy}tetrahydro-2H-pyran-2-yl)oxy]methyl}-5-hydroxy-3-{[(3R)-3-hydroxytetradecanoyl]amino}-4-{[(3R)-3-hydroxytetradecyl]oxy}tetrahydro-2H-pyran-2-carboxylic acid