| CAS号 | 171599-83-0 |
| 中文别名 | 拘橼酸西地那非;西地那非(柠檬酸盐);1-[[3-(6,7-二氢-1-甲基-7-氧-3-丙基-1H-吡唑并-[4,3-d]嘧啶-5-基)-4-乙氧苯基]璜酰基]-4-甲基哌嗪柠檬酸盐;伟哥;西地那非柠檬酸盐;万艾可;西地那非(枸橼酸盐) |
| 英文别名 | 1-[[3-(4,7-DIHYDRO-1-METHYL-7-OXO-3-PROPYL-1H-PYRAZOLO[4,3-D]PYRIMIDIN-5-YL)-4-ETHOXYPHENYL]SULFONYL]-4-METHYLPIPERAZINE, CITRATE; 1-[[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1h-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate; VIAGRA; din-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methyl-,2-hydroxy-1,2,3-propanetricarbo; piperazine,1-((3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1h-pyrazolo(4,3-d)pyrimi; piperazine,1-((3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1h-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methyl-,2-hydroxy-1,2,3-propanetricarboxylate(1:1); uk92480-10; SILDANAFIL CITRATE (BULK); SildenafilBaseC28H38N6O11S; SildenafilCitrate/SildenafilBaseC28H38N6O11S; 1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine, Citrate; SILDENAFIL CITRATE(RG); 5(2-ETHOXY-5(4-METHYLPIPERAZINE)SULPHONYLPHENYL)-1; 1-[[3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate |
| 分子量 | 666.69992 |
| 分子式 | C22H30N6O4S.C6H8O7 |
| EINECS编号 |
枸橼酸西地那非物理化学性质
外观：白色或类白色结晶性粉末， ，无色，无味
密度：1.447g/cm3
熔点：187-189°C
沸点：672.4 °C at 760 mmHg
蒸气：0mmHg at 25°C
折射率：1.683
闪点：360.5°C
溶解度：不溶于水，乙醇，易溶于二甲基甲酰胺
蒸汽压：0mmHg
枸橼酸西地那非产品用途
枸橼酸西地那非是医药中间体。
枸橼酸西地那非是一种对环磷酸鸟苷（cGMP）特异的5型磷酸二酯酶（PDE5）选择性抑制剂，作为治疗阳痿的专用药物。
枸橼酸西地那非计算化学数据
Molecular Weight:474.5764 [g/mol]
Molecular Formula:C22H30N6O4S
XLogP3-AA:1.5
H-Bond Donor:1
H-Bond Acceptor:7
Rotatable Bond Count:7
Tautomer Count:3
Exact Mass:474.204924
MonoIsotopic Mass:474.204924
Topological Polar Surface Area:118
Heavy Atom Count:33
Formal Charge:0
Complexity:838
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1
Feature 3D Acceptor Count:5
Feature 3D Donor Count:2
Feature 3D Cation Count:1
Feature 3D Hydrophobe Count:1
Feature 3D Ring Count:4
Effective Rotor Count:8.2
Conformer Sampling RMSD:1
CID Conformer Count:76
刺激眼睛、呼吸系统和皮肤。
