上游原料
2,5-Furandione; Maleic anhydridecyclohexa-1,3-diene;1,3-Cyclohexanediene4,7-Ethanoisobenzofuran-1,3-dione,hexahydro-;(3aS,4R,7R)-hexahydro-4,7-ethanoisobenzofuran-1,3-dione(1R,2S,4R)-3-(methoxycarbonyl)bicyclo[2.2.2]octane-2-carboxylic acidmethyl(1R,3S,4R)-3-(((benzyloxy)carbonyl)amino)bicyclo[2.2.2]octane-2-carboxylate(1R,3S,4R)-3-aminobicyclo[2.2.2]octane-2-carboxylate2,4-dichloro-5-fluoropyrimidine；2,4-Dichloro-5-fluorouracilmethyl(1R,2S,3S,4R)-3-((2-chloro-5-fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylatemethyl(1R,2S,3S,4R)-3-((2-chloro-5-fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylate5-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridinemethyl(1R,2S,3S,4R)-3-((5-fluoro-2-(5-fluoro-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylatemethyl(1R,2S,3S,4R)-3-((5-fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylate3-bromo-5-fluoro-1H-pyrrolo[2,3-b]pyridine3-bromo-5-fluoro-1-tosyl-1H-pyrrolo[2,3-b]pyridine5-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine2-chloro-5-fluoro-4-(methylsulfanyl)pyrimidine5-fluoro-3-(5-fluoro-4-(methylthio)pyrimidin-2-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine5-fluoro-3-(5-fluoro-4-(methylsulfinyl)pyrimidin-2-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridinemethyl(1R,2S,3S,4R)-3-nitrobicyclo[2.2.2]octane-2-carboxylate(1R,3S,4R)-3-aminobicyclo[2.2.2]octane-2-carboxylatemethyl(1R,2S,3S,4R)-3-((5-fluoro-2-(5-fluoro-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylate5-fluoro-2-pyridinamine; 5-fluoro-2-pyridinylamine5-fluoro-3-iodopyridin-2-amine3-bromo-5-fluoropyridin-2-amineethynyl(trimethyl)silane；trimethylsilyl acetylene5-fluoro-3-((trimethylsilyl)ethynyl)pyridin-2-amine3-ethynyl-5-fluoropyridin-2-amine5-fluoro-1H-pyrrolo[2,3-b]pyridineAcetaldehyde5-fluoro-1-tosyl-1H-pyrrolo[2,3-b]pyridine3-bromo-5-fluoro-1-tosyl-1H-pyrrolo[2,3-b]pyridine5-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine(1R,3S,4R)-3-((2-chloro-5-fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid(1R,3S,4R)-3-((5-fluoro-2-(5-fluoro-1-tosyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid(3aS,4R,7S)-3a,4,7,7a-tetrahydro-4,7-ethanoisobenzofuran-1,3-dione; 4,7-Ethanoisobenzofuran-1,3-dione,3a,4,7,7a-tetrahydro-, (3aR,4S,7R,7aS)-rel-(1S,3S,4R)-3-(ethoxycarbonyl)bicyclo[2.2.2]oct-5-ene-2-carboxylic acid(1S,2S,3S,4R)-3-(ethoxycarbonyl)bicyclo[2.2.2]oct-5-ene-2-carboxylic acidethyl(1R,3S,4S)-3-(((benzyloxy)carbonyl)amino)bicyclo[2.2.2]oct-5-ene-2-carboxylateethyl(1R,3S,4S)-3-aminobicyclo[2.2.2]oct-5-ene-2-carboxylate hydrochloride2,4-dichloro-5-fluoropyrimidine；2,4-Dichloro-5-fluorouracilethyl(1R,3S,4S)-3-((2-chloro-5-fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]oct-5-ene-2-carboxylateethyl propiolatecyclohexa-1,3-diene;1,3-Cyclohexanedieneethyl(1R,4S)-bicyclo[2.2.2]octa-2,5-diene-2-carboxylateethyl(1s,4s)-bicyclo[2.2.2]oct-2-ene-2-carboxylateethyl(1R,2S,3S,4R)-3-(benzyl((S)-1-phenylethyl)amino)bicyclo[2.2.2]octane-2-carboxylate(1R)-N-benzyl-1-phenyl-1-ethanamine; N-benzyl-N-[(1R)-1-phenylethyl]amineN-Benzyl-N-(1(S)-phenylethyl)amide lithium salt(1R,3S,4R)-3-((2-chloro-5-fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid5-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridineethyl(1R,3S,4S)-3-((2-chloro-5-fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]oct-5-ene-2-carboxylateethyl(1R,2S,3S,4R)-3-((5-fluoro-2-(5-fluoro-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylateethyl(1R,2S,3S,4R)-3-((5-fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylate hydrochloride
