上游原料
o-bromobenzonitrile; 2-bromobenzonitrileDiethyl 2-acetylglutarate; diethyl 2-acetylpentanedioateethanimidamideethyl 3-(2,4-dimethyl-6-oxo-1,6-dihydro-5-pyrimidinyl)propanoateethyl 3-(4-chloro-2,6-dimethyl-5-pyrimidinyl)propanoate4-bromobenzylamine; (4-bromophenyl)methanamine8-(4-bromobenzyl)-2,4-dimethyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one2-[2-(tert-butyl)-2H-1,2,3,4-tetraazol-5-yl]phenylboronic acid8-([2'-[2-(tert-butyl)-2H-1,2,3,4-tetraazol-5-yl][1,1'-biphenyl]-4-yl]methyl)-2,4-dimethyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one5-(2-bromophenyl)-2-(tert-butyl)-2H-1,2,3,4-tetraazole8-(4-bromobenzyl)-2,4-dimethyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one8-([2'-[2-(tert-butyl)-2H-1,2,3,4-tetraazol-5-yl][1,1'-biphenyl]-4-yl]methyl)-2,4-dimethyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one5-(2-bromophenyl)-2-(tert-butyl)-2H-1,2,3,4-tetraazole[2-[2-(tert-butyl)-2H-1,2,3,4-tetraazol-5-yl]phenyl](chloro)zincmethyl (2S,3S,4S,5R,6R)-3,4,5-tris(acetoxy)-6-bromotetrahydro-2H-pyran-2-carboxylate5-hydroxy-2,4-dimethyl-8-[[2'-(1H-1,2,3,4-tetraazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-onesodium (2S,3S,4S,5R,6R)-6-[5-(4'-[[2,4-dimethyl-7-oxo-6,7-dihydropyrido[2,3-d]pyrimidin-8(5H)-yl]methyl][1,1'-biphenyl]-2-yl)-2H-1,2,3,4-tetraazol-2-yl]-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate2,4-dimethyl-8-[[2'-(1H-1,2,3,4-tetraazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-onemethyl (2S,3R,4S,5R,6R)-3,4,5-tris(acetoxy)-6-[5-(4'-[[2,4-dimethyl-7-oxo-6,7-dihydropyrido[2,3-d]pyrimidin-8(5H)-yl]methyl][1,1'-biphenyl]-2-yl)-2H-1,2,3,4-tetraazol-2-yl]tetrahydro-2H-pyran-2-carboxylatemethyl (2S,3S,4S,5R,6R)-6-[5-(4'-[[2,4-dimethyl-7-oxo-6,7-dihydropyrido[2,3-d]pyrimidin-8(5H)-yl]methyl][1,1'-biphenyl]-2-yl)-2H-1,2,3,4-tetraazol-2-yl]-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate4-bromobenzylamine; (4-bromophenyl)methanamine2-[2-(tert-butyl)-2H-1,2,3,4-tetraazol-5-yl]phenylboronic acidethyl 1-(tributylstannyl)vinyl ether; tributyl(1-ethoxyvinyl)stannane5-hydroxy-2,4-dimethyl-8-[[2'-(1H-1,2,3,4-tetraazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]pyrido[2,3-d]pyrimidin-7(8H)-one2,6-dimethyl-4-pyrimidinol5-iodo-2,6-dimethyl-4-pyrimidinol4-chloro-5-iodo-2,6-dimethylpyrimidine1-(4-chloro-2,6-dimethyl-5-pyrimidinyl)vinyl ethyl ether; 4-chloro-5-(1-ethoxyvinyl)-2,6-dimethylpyrimidineN-(4-bromobenzyl)-5-(1-ethoxyvinyl)-2,6-dimethyl-4-pyrimidinamine; N-(4-bromobenzyl)-N-[5-(1-ethoxyvinyl)-2,6-dimethyl-4-pyrimidinyl]amine1-[4-[(4-bromobenzyl)amino]-2,6-dimethyl-5-pyrimidinyl]-1-ethanone1-[4-[([2'-[2-(tert-butyl)-2H-1,2,3,4-tetraazol-5-yl][1,1'-biphenyl]-4-yl]methyl)amino]-2,6-dimethyl-5-pyrimidinyl]-1-ethanone8-([2'-[2-(tert-butyl)-2H-1,2,3,4-tetraazol-5-yl][1,1'-biphenyl]-4-yl]methyl)-5-hydroxy-2,4-dimethylpyrido[2,3-d]pyrimidin-7(8H)-one4'-(bromomethyl)[1,1'-biphenyl]-2-carbonitrile; 4'-bromomethyl-2-cyanobiphenyl2,4-dimethylpyrido[2,3-d]pyrimidin-7(8H)-one4'-[[2,4-dimethyl-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl]methyl][1,1'-biphenyl]-2-carbonitrile2,4-dimethyl-8-[[2'-(1H-1,2,3,4-tetraazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]pyrido[2,3-d]pyrimidin-7(8H)-one
