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2H-4,8-Methenop...
CAS号 1454846-35-5
中文别名
英文别名 7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11)benzoxadiazacyclotetradecine-3-carbonitrile;Loratinib;PF 06463922;PF-06463922;UNII-OSP71S83EU;Loratinib [USAN];PF-06463922
分子量 406.4191
分子式 C21H19FN6O2
EINECS编号
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上游原料
Ethyl 1,3-dimethyl-1H-pyrazole-5-carboxylateEthyl 4-bromo-3-(bromomethyl)-1-methyl-1H-pyrazole-5-carboxylateMethanamine; MethylamineEthyl 4-bromo-1-methyl-3-((methylamino)methyl)-1H-pyrazole-5-carboxylateEthyl 4-bromo-3-(((tert-butoxycarbonyl)(methyl)amino)methyl)-1-methyl-1H-pyrazole-5-carboxylatetert-butyl methylcarbamate4-bromo-3-(((tert-butoxycarbonyl)(methyl)amino)methyl)-1-methyl-1H-pyrazole-5-carboxylic acidtert-butyl ((4-bromo-5-carbamoyl-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamatetert-butyl ((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamatetert-butyl ((5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate1-methyl-3-((methylamino)methyl)-1H-pyrazole-5-carbonitrile(R)-3-(1-(5-fluoro-2-iodophenyl)ethoxy)pyridin-2-amine(R)-2-(1-((2-aminopyridin-3-yl)oxy)ethyl)-N-((5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)-4-fluoro-N-methylbenzamide(R)-2-(1-((2-amino-5-bromopyridin-3-yl)oxy)ethyl)-N-((5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)-4-fluoro-N-methylbenzamide(R)-2-(1-((2-(N-acetylacetamido)-5-bromopyridin-3-yl)oxy)ethyl)-N-((5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)-4-fluoro-N-methylbenzamide5-fluoro-2-iodoacetophenone(S)-1-(5-fluoro-2-iodophenyl)ethan-1-ol(S)-1-(5-fluoro-2-iodophenyl)ethyl methanesulfonate2-amino-3-pyridinol; 2-Amino-3-hydroxypyridine(R)-3-(1-(5-fluoro-2-iodophenyl)ethoxy)pyridin-2-amineMethyl (R)-2-(1-((2-aminopyridin-3-yl)oxy)ethyl)-4-fluorobenzoateMethyl (R)-2-(1-((2-amino-5-bromopyridin-3-yl)oxy)ethyl)-4-fluorobenzoatetert-butyl ((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamateMethyl (R)-2-(1-((2-amino-5-(3-(((tert-butoxycarbonyl)(methyl)amino)methyl)-5-cyano-1-methyl-1H-pyrazol-4-yl)pyridin-3-yl)oxy)ethyl)-4-fluorobenzoate(R)-2-(1-((2-amino-5-(3-(((tert-butoxycarbonyl)(methyl)amino)methyl)-5-cyano-1-methyl-1H-pyrazol-4-yl)pyridin-3-yl)oxy)ethyl)-4-fluorobenzoic acid(R)-2-(1-((2-amino-5-(5-cyano-1-methyl-3-((methylamino)methyl)-1H-pyrazol-4-yl)pyridin-3-yl)oxy)ethyl)-4-fluorobenzoic acidMethyl 4-bromo-1,3-dimethyl-1H-pyrazole-5-carboxylate4-bromo-1,3-dimethyl-1H-pyrazole-5-carboxamide4-bromo-1,3-dimethyl-1H-pyrazole-5-carbonitrile4-bromo-3-(bromomethyl)-1-methyl-1H-pyrazole-5-carbonitrileMethanamine; Methylamine4-bromo-1-methyl-3-((methylamino)methyl)-1H-pyrazole-5-carbonitriletert-butyl ((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate1-Chloroacetone; ChloroacetoneN-Methyl(phenyl)methanamine; N-Benzyl-N-methylamine; N-Methylbenzylamine1-(benzyl(methyl)amino)propan-2-onetert-butyl methyl(2-oxopropyl)carbamateDiethyl oxalate; Ethyl 2-ethoxy-2-oxoacetate1-Methylhydrazine; Monomethyl hydrazineMethyl 3-(((tert-butoxycarbonyl)(methyl)amino)methyl)-1-methyl-1H-pyrazole-5-carboxylatetert-butyl ((5-carbamoyl-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamatetert-butyl ((5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate1-methyl-3-((methylamino)methyl)-1H-pyrazole-5-carbonitrile hydrochlorideMethyl (R)-2-(1-((2-amino-5-bromopyridin-3-yl)oxy)ethyl)-4-fluorobenzoate