上游原料
(4R)-4-[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-3-[(tetrahydro-2H-pyran-2-yloxy)methyl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentyl 4-methylbenzenesulfonate[(3S,8S,9S,10R,13R,14S,17R)-17-[(1R)-4-Bromo-1-methylbutyl]-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]methyl tetrahydro-2H-pyran-2-yl ether(6R)-6-[(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-3-[(tetrahydro-2H-pyran-2-yloxy)methyl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-1,1,1-trifluoro-2-(trifluoromethyl)-2-heptanol2-([(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-[(1R)-1-methyl-4-(phenylsulfonyl)butyl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]methoxy)tetrahydro-2H-pyran; (4R)-4-[(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-3-[(tetrahydro-2H-pyran-2-yloxy)methyl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentyl phenyl sulfone(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-[(1R)-6,6,6-trifluoro-5-hydroxy-1-methyl-5-(trifluoromethyl)hexyl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol(8S,9S,10S,13R,14S,17R)-10,13-Dimethyl-17-[(1R)-6,6,6-trifluoro-5-hydroxy-1-methyl-5-(trifluoromethyl)hexyl]-8,9,10,11,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one(2aR,3aR,3bR,3cS,5aR,6R,8aS,8bS)-3b,5a-Dimethyl-6-[(1R)-6,6,6-trifluoro-5-hydroxy-1-methyl-5-(trifluoromethyl)hexyl]-2a,3a,3b,3c,4,5,5a,6,7,8,8a,8b-dodecahydro-2H-cyclopenta[7,8]phenanthro[3,4-b]oxiren-2-one(1S,3R,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-[(1R)-6,6,6-trifluoro-5-hydroxy-1-methyl-5-(trifluoromethyl)hexyl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-1,3-diol(1S,3R,8S,9S,10R,13R,14S,17R)-1-(acetoxy)-17-[(1R)-5-(acetoxy)-6,6,6-trifluoro-1-methyl-5-(trifluoromethyl)hexyl]-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate(1S,3R,9S,10R,13R,14R,17R)-1-(acetoxy)-17-[(1R)-5-(acetoxy)-6,6,6-trifluoro-1-methyl-5-(trifluoromethyl)hexyl]-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate(1R,5S)-3-((Z)-2-[(1R,3aR,7aR)-1-[(1R)-5-(acetoxy)-6,6,6-trifluoro-1-methyl-5-(trifluoromethyl)hexyl]-7a-methyloctahydro-4H-inden-4-ylidene]ethylidene)-5-(acetoxy)-4-methylenecyclohexyl acetate(1S,3R,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-[(1R)-6,6,6-trifluoro-5-hydroxy-1-methyl-5-(trifluoromethyl)hexyl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-1,3-diolmethyl (4R)-4-[(3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate; 3beta-Hydroxichol-5-en-24-oic acid methyl estermethyl (4R)-4-[(8S,9S,10S,13R,14S,17R)-10,13-dimethyl-3-oxo-8,9,10,11,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-17-yl]pentanoatemethyl (4R)-4-[(2aR,3aR,3bR,3cS,5aR,6R,8aS,8bS)-3b,5a-dimethyl-2-oxo-2a,3a,3b,3c,4,5,5a,6,7,8,8a,8b-dodecahydro-2H-cyclopenta[7,8]phenanthro[3,4-b]oxiren-6-yl]pentanoate(1S,3R,8S,9S,10R,13R,14S,17R)-17-[(1R)-4-Hydroxy-1-methylbutyl]-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-1,3-diol(1S,3R,8S,9S,10R,13R,14S,17R)-1-(acetoxy)-17-[(1R)-4-hydroxy-1-methylbutyl]-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate(1S,3R,8S,9S,10R,13R,14S,17R)-1-(acetoxy)-17-[(1R)-4-bromo-1-methylbutyl]-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate(1S,3R,8S,9S,10R,13R,14S,17R)-1-(acetoxy)-10,13-dimethyl-17-[(1R)-1-methyl-4-(phenylsulfonyl)butyl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate(4R)-4-[(1S,3S,8S,9S,10S,13R,14S,17R)-10,13-Dimethyl-1,3-bis[(trimethylsilyl)methyl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentyl phenyl sulfone; ([(1S,3S,8S,9S,10S,13R,14S,17R)-10,13-Dimethyl-17-[(1R)-1-methyl-4-(phenylsulfonyl)butyl]-3-[(trimethylsilyl)methyl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-1-yl]methyl)(trimethyl)silane(6R)-6-[(1S,3S,8S,9S,10S,13R,14S,17R)-10,13-Dimethyl-1,3-bis[(trimethylsilyl)methyl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-1,1,1-trifluoro-3-(phenylsulfonyl)-2-(trifluoromethyl)-2-heptanol(3R)-3-[(1R,3aR,7aR)-4-[(E)-2-((3S,5R)-3,5-bis[[tert-butyl(dimethyl)silyl]oxy]-2-methylenecyclohexylidene)ethylidene]-7a-methyloctahydro-1H-inden-1-yl]butanal1,1,1,3,3,3-hexafluoroacetone(4R)-4-{(1R,3aR,7aR)-4-[(E)-2-((3S,5R)-3,5-bis{[tert-butyl(dimethyl)silyl]oxy}-2-methylenecyclohexylidene)ethylidene]-7a-methyloctahydro-1H-inden-1-yl}-2-pentanol(4R)-4-{(1R,3aR,7aR)-4-[(E)-2-((3S,5R)-3,5-bis{[tert-butyl(dimethyl)silyl]oxy}-2-methylenecyclohexylidene)ethylidene]-7a-methyloctahydro-1H-inden-1-yl}-2-pentanone(6R)-6-{(1R,3aR,7aR)-4-[(E)-2-((3S,5R)-3,5-bis{[tert-butyl(dimethyl)silyl]oxy}-2-methylenecyclohexylidene)ethylidene]-7a-methyloctahydro-1H-inden-1-yl}-1,1,1-trifluoro-2-hydroxy-2-(trifluoromethyl)-4-heptanone(6R)-6-{(1R,3aR,7aR)-4-[(E)-2-((3S,5R)-3,5-bis{[tert-butyl(dimethyl)silyl]oxy}-2-methylenecyclohexylidene)ethylidene]-7a-methyloctahydro-1H-inden-1-yl}-1,1,1-trifluoro-2-(trifluoromethyl)-2,4-heptanediol1-((2R)-2-{(1R,3aR,7aR)-4-[(E)-2-((3S,5R)-3,5-bis{[tert-butyl(dimethyl)silyl]oxy}-2-methylenecyclohexylidene)ethylidene]-7a-methyloctahydro-1H-inden-1-yl}propyl)-4,4,4-trifluoro-3-hydroxy-3-(trifluoromethyl)butyl acetate1-((2R)-2-{(1R,3aR,7aR)-4-[(E)-2-((3S,5R)-3,5-bis{[tert-butyl(dimethyl)silyl]oxy}-2-methylenecyclohexylidene)ethylidene]-7a-methyloctahydro-1H-inden-1-yl}propyl)-4,4,4-trifluoro-3-(methoxymethoxy)-3-(trifluoromethyl)butyl acetate(6R)-6-{(1R,3aR,7aR)-4-[(E)-2-((3S,5R)-3,5-bis{[tert-butyl(dimethyl)silyl]oxy}-2-methylenecyclohexylidene)ethylidene]-7a-methyloctahydro-1H-inden-1-yl}-1,1,1-trifluoro-2-(methoxymethoxy)-2-(trifluoromethyl)-4-heptanolO-[1-((2R)-2-{(1R,3aR,7aR)-4-[(E)-2-((3S,5R)-3,5-bis{[tert-butyl(dimethyl)silyl]oxy}-2-methylenecyclohexylidene)ethylidene]-7a-methyloctahydro-1H-inden-1-yl}propyl)-4,4,4-trifluoro-3-(methoxymethoxy)-3-(trifluoromethyl)butyl] S-methyl carbonodithioa(1R,5S)-3-((Z)-2-{(1R,3aR,7aR)-7a-methyl-1-[(1R)-6,6,6-trifluoro-5-(methoxymethoxy)-1-methyl-5-(trifluoromethyl)hexyl]octahydro-4H-inden-4-ylidene}ethylidene)-5-{[tert-butyl(dimethyl)silyl]oxy}-4-methylenecyclohexyl tert-butyl(dimethyl)silyl ether; [((1R,5S)-3-((Z)-2-{(1R,3aR,7aR)-7a-methyl-1-[(1R)-6,6,6-trifluoro-5-(methoxymethoxy)-1-methyl-5-(trifluoromethyl)hexyl]octahydro-4H-inden-4-ylidene}ethylidene)-5-{[tert-butyl(dimethyl)silyl]oxy}-4-methylenecyclohexyl)oxy](tert-butyl)dimethylsilane
